Dr. LIU Xidan

劉希丹

Post-doctoral Fellow

PhD

Field of Research

Metabolic disease mechanisms with a focus on adipose biology. Translational research on adipose tissue dysfunction in cancer and metabolic syndromes.

Biography

Dr. Xidan Liu is a Postdoctoral Fellow at the Faculty of Medicine, The University of Hong Kong. She received his Bachelor’s degree in Marine Science from Zhejiang University (2015-2019) and her Ph.D. in Biology (Molecular Medicine) from Peking University (2019-2024). She worked as a Scientific Researcher at Guangdong Provincial People’s Hospital (2024-2025). Her research focuses on the mechanisms of metabolic diseases, with seminal work in cancer cachexia that includes the first demonstration of tumor-derived lactate’s endocrine function via GPR81 to trigger systemic energy imbalance, and the discovery of the MIF-ACKR3 axis as a master regulator of adipogenesis.

Publications

Liu X*, Li S*, Cui Q*, Guo B, Ding W, Liu J, Quan L, Li X, Xie P, Jin L, Sheng Y, Chen W, Wang K, Zeng F, Qiu Y, Liu C, Zhang Y, Lv F, Hu X#, Xiao RP#. Activation of GPR81 by lactate drives tumour-induced cachexia. Nature Metabolism. 2024 Apr;6(4):708-723. (IF 20.8, JCR ranking Q1, 4/186, ENDOCRINOLOGY & METABOLISM-SCIE, co-first author)
Cui Q*, Li S*, Liu X*, Jie Liu*, Chen W, Sheng Y, Xie P, Jin L, Zeng F, Lv F, Hu X#, Xiao RP#. MIF-ACKR3 Causes Irreversible Fat Loss by Impairing Adipogenesis in Cancer Cachexia. Cell Metabolism. 2025 Feb 26:S1550-4131(25)00018-X. (IF 27.7, JCR ranking Q1, 2/186, ENDOCRINOLOGY & METABOLISM-SCIE, co-first author)
Zhang D, Liu X, Huang Wei, Li J, Wang C, Zhang D, Zhang C. Microplastic pollution in deep-sea sediments and organisms of the Western Pacific Ocean. Environmental pollution. 2020 Apr;259:113948. (IF 7.6, JCR ranking Q1, 35/359, ENVIRONMENTAL SCIENCES-SCIE, second author)

Awards: Outstanding Graduate of Beijing and Peking University (JUN, 2024);

Conferences attended: Coordinator and Institutional Liaison of NSFC Key Project Workshop on Pulmonary Hypertension (Jan 2025).